منابع مشابه
Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A
Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-year-old female with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinical course. A diagnostic workup revealed AIHA and PRCA as...
متن کاملEpoetin-induced autoimmune pure red cell aplasia.
During the first 10 yr of therapy with recombinant human erythropoietin ([EPO]), only three cases of antibody-associated pure red cell aplasia have been described in patients who were treated with EPO, whereas several millions of patients have received this treatment. Thus, the possibility for epoetin to induce the formation of anti-EPO antibodies was considered extremely low. However, since 19...
متن کاملB-cell prolymphocytic leukemia carrying t(8;14)(q24;q32), associated with both autoimmune hemolytic anemia and pure red cell aplasia.
An 80-year-old man was referred to our department because of lymphocytosis. His white cell count was 17.1 × 10(3)/μL, with 64% prolymphocytes. He did not exhibit splenomegaly or lymphadenopathy. Prolymphocytes were CD5(+), CD10(-), CD19(+), CD20(+), CD21(+weak), CD22(+), CD23(-), and HLA-DR(+), and expressed μδ/λ cell-surface immunoglobulins. G-banding and fluorescence in situ hybridization usi...
متن کاملPure red cell aplasia as an autoimmune receptor disease.
To the Editor: Suppression of the erythroblastic compartment in the bone marrow is the hallmark of pure red cell aplasiaL2 (PRCA). The demonstration of IgG inhibitors of erythropoiesis2 has given a clear indication of the autoimmune pathogenesis of the disease. Indeed, two types of PRCA have been distinguished recently,5 the first with autoantibodies directed against the erythroid marrow and th...
متن کاملMyelodysplastic Syndrome with Erythroid Aplasia following Pure Red Cell Aplasia
Myelodysplastic syndrome (MDS) with erythroid aplasia is a very rare disorder that has not been clearly defined. We experienced a case of pure red cell aplasia (PRCA), which evolved to MDS with erythroid aplasia. A 59-year-old male with transfusion-dependent PRCA was referred to our hospital for an evaluation of newly developed thrombocytopenia. Two years ago, PRCA was diagnosed by the laborato...
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ژورنال
عنوان ژورنال: Journal of Postgraduate Medicine
سال: 2013
ISSN: 0022-3859
DOI: 10.4103/0022-3859.109495